Metaplasia of the lung respiratory epithelium and antibody dynamics in mice repeatedly infected with various subtypes of influenza virus A.
Identifieur interne : 002490 ( Main/Exploration ); précédent : 002489; suivant : 002491Metaplasia of the lung respiratory epithelium and antibody dynamics in mice repeatedly infected with various subtypes of influenza virus A.
Auteurs : J. Wilczy Ski ; S. Kru ; R. Semkow ; M. Loza-TulimowskaSource :
- Acta microbiologica Polonica [ 0137-1320 ] ; 1984.
Descripteurs français
- KwdFr :
- Animaux, Anticorps antiviraux (biosynthèse), Infections à Orthomyxoviridae (anatomopathologie), Infections à Orthomyxoviridae (immunologie), Métaplasie, Poumon (anatomopathologie), Souris, Spécificité des anticorps, Virus de la grippe A (), Virus de la grippe A (immunologie), Épithélium (anatomopathologie).
- MESH :
- anatomopathologie : Infections à Orthomyxoviridae, Poumon, Épithélium.
- biosynthèse : Anticorps antiviraux.
- immunologie : Infections à Orthomyxoviridae, Virus de la grippe A.
- Animaux, Métaplasie, Souris, Spécificité des anticorps, Virus de la grippe A.
English descriptors
- KwdEn :
- MESH :
- chemical , biosynthesis : Antibodies, Viral.
- classification : Influenza A virus.
- immunology : Influenza A virus, Orthomyxoviridae Infections.
- pathology : Epithelium, Lung, Orthomyxoviridae Infections.
- Animals, Antibody Specificity, Metaplasia, Mice.
Abstract
Mice were repeatedly infected with consecutive doses of mouse-adapted strains of influenza virus A HON1, H1N1, H2N2, and H3N2. Homo- and heterologous antibody levels as well as the incidence of metaplasia were followed. Statistically significant correlation was found between the metaplasia incidence and higher level of antibodies homologous to virus used for a given challenge dose.
PubMed: 6205549
Affiliations:
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Le document en format XML
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<author><name sortKey="Loza Tulimowska, M" sort="Loza Tulimowska, M" uniqKey="Loza Tulimowska M" first="M" last="Loza-Tulimowska">M. Loza-Tulimowska</name>
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<author><name sortKey="Kru, S" sort="Kru, S" uniqKey="Kru S" first="S" last="Kru">S. Kru</name>
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<author><name sortKey="Loza Tulimowska, M" sort="Loza Tulimowska, M" uniqKey="Loza Tulimowska M" first="M" last="Loza-Tulimowska">M. Loza-Tulimowska</name>
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<term>Antibodies, Viral (biosynthesis)</term>
<term>Antibody Specificity</term>
<term>Epithelium (pathology)</term>
<term>Influenza A virus (classification)</term>
<term>Influenza A virus (immunology)</term>
<term>Lung (pathology)</term>
<term>Metaplasia</term>
<term>Mice</term>
<term>Orthomyxoviridae Infections (immunology)</term>
<term>Orthomyxoviridae Infections (pathology)</term>
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<keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term>
<term>Anticorps antiviraux (biosynthèse)</term>
<term>Infections à Orthomyxoviridae (anatomopathologie)</term>
<term>Infections à Orthomyxoviridae (immunologie)</term>
<term>Métaplasie</term>
<term>Poumon (anatomopathologie)</term>
<term>Souris</term>
<term>Spécificité des anticorps</term>
<term>Virus de la grippe A ()</term>
<term>Virus de la grippe A (immunologie)</term>
<term>Épithélium (anatomopathologie)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="biosynthesis" xml:lang="en"><term>Antibodies, Viral</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Infections à Orthomyxoviridae</term>
<term>Poumon</term>
<term>Épithélium</term>
</keywords>
<keywords scheme="MESH" qualifier="biosynthèse" xml:lang="fr"><term>Anticorps antiviraux</term>
</keywords>
<keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>Influenza A virus</term>
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<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Infections à Orthomyxoviridae</term>
<term>Virus de la grippe A</term>
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<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Influenza A virus</term>
<term>Orthomyxoviridae Infections</term>
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<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Epithelium</term>
<term>Lung</term>
<term>Orthomyxoviridae Infections</term>
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<term>Antibody Specificity</term>
<term>Metaplasia</term>
<term>Mice</term>
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<term>Métaplasie</term>
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<front><div type="abstract" xml:lang="en">Mice were repeatedly infected with consecutive doses of mouse-adapted strains of influenza virus A HON1, H1N1, H2N2, and H3N2. Homo- and heterologous antibody levels as well as the incidence of metaplasia were followed. Statistically significant correlation was found between the metaplasia incidence and higher level of antibodies homologous to virus used for a given challenge dose.</div>
</front>
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<affiliations><list></list>
<tree><noCountry><name sortKey="Kru, S" sort="Kru, S" uniqKey="Kru S" first="S" last="Kru">S. Kru</name>
<name sortKey="Loza Tulimowska, M" sort="Loza Tulimowska, M" uniqKey="Loza Tulimowska M" first="M" last="Loza-Tulimowska">M. Loza-Tulimowska</name>
<name sortKey="Semkow, R" sort="Semkow, R" uniqKey="Semkow R" first="R" last="Semkow">R. Semkow</name>
<name sortKey="Wilczy Ski, J" sort="Wilczy Ski, J" uniqKey="Wilczy Ski J" first="J" last="Wilczy Ski">J. Wilczy Ski</name>
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