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Metaplasia of the lung respiratory epithelium and antibody dynamics in mice repeatedly infected with various subtypes of influenza virus A.

Identifieur interne : 002490 ( Main/Exploration ); précédent : 002489; suivant : 002491

Metaplasia of the lung respiratory epithelium and antibody dynamics in mice repeatedly infected with various subtypes of influenza virus A.

Auteurs : J. Wilczy Ski ; S. Kru ; R. Semkow ; M. Loza-Tulimowska

Source :

RBID : pubmed:6205549

Descripteurs français

English descriptors

Abstract

Mice were repeatedly infected with consecutive doses of mouse-adapted strains of influenza virus A HON1, H1N1, H2N2, and H3N2. Homo- and heterologous antibody levels as well as the incidence of metaplasia were followed. Statistically significant correlation was found between the metaplasia incidence and higher level of antibodies homologous to virus used for a given challenge dose.

PubMed: 6205549


Affiliations:


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<term>Epithelium (pathology)</term>
<term>Influenza A virus (classification)</term>
<term>Influenza A virus (immunology)</term>
<term>Lung (pathology)</term>
<term>Metaplasia</term>
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<term>Orthomyxoviridae Infections (immunology)</term>
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<term>Souris</term>
<term>Spécificité des anticorps</term>
<term>Virus de la grippe A ()</term>
<term>Virus de la grippe A (immunologie)</term>
<term>Épithélium (anatomopathologie)</term>
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<term>Infections à Orthomyxoviridae</term>
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